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UniProt functional annotation for P00644 | ||
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| UniProt code: P00644. |
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| Organism: | |
Staphylococcus aureus. |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus. |
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| Function: | |
Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. |
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| Catalytic activity: | |
Reaction=Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'- phosphooligonucleotide end-products.; EC=3.1.31.1; Evidence={ECO:0000255|PROSITE-ProRule:PRU10048, ECO:0000255|PROSITE- ProRule:PRU10049}; |
| Cofactor: | |
Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Note=Binds 1 Ca(2+) ion per subunit.; |
| Subcellular location: | |
[Nuclease A]: Secreted. |
| Subcellular location: | |
[Nuclease B]: Membrane. |
| Similarity: | |
Belongs to the thermonuclease family. {ECO:0000255|PROSITE- ProRule:PRU00272}. |
| Sequence caution: | |
Sequence=AAA26659.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.