UniProt functional annotation for P0A998

UniProt code: P0A998.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: Iron-storage protein. {ECO:0000269|PubMed:11254384}.
 
Catalytic activity: Reaction=4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-hydroxide; Xref=Rhea:RHEA:11972, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:29033, ChEBI:CHEBI:78619; EC=1.16.3.2; Evidence={ECO:0000269|PubMed:24380371};
Subunit: Homooligomer of 24 subunits that assemble into a spherical protein shell (12 +/- 1 nM diameter) that can sequester at least 2000 iron atoms. {ECO:0000269|PubMed:11254384, ECO:0000269|PubMed:8281950}.
Subcellular location: Cytoplasm.
Similarity: Belongs to the ferritin family. Prokaryotic subfamily. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.