| UniProt functional annotation for P78285 | |||
| UniProt code: P78285. |
| Organism: | Escherichia coli (strain K12). | |
| Taxonomy: | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. | |
| Function: | Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity. Exhibits lytic activity against E.coli and S.typhi cell wall substrate. {ECO:0000269|PubMed:17914239}. | |
| Catalytic activity: | Reaction=Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.; EC=3.2.1.17; | |
| Disruption phenotype: | Mutants are unable to form wild-type biofilms, which could be due to altered peptidoglycan metabolism. {ECO:0000269|PubMed:21415116}. | |
| Miscellaneous: | Encoded by the cryptic lambdoid prophage DLP12. | |
| Similarity: | Belongs to the glycosyl hydrolase 24 family. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.