UniProt functional annotation for P9WKV2



	UniProt functional annotation for P9WKV2

UniProt code: P9WKV2.

Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).

Taxonomy: Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex.

Function: Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems (By similarity). {ECO:0000250}.

Pathway: Cell wall biogenesis; peptidoglycan biosynthesis.

Disruption phenotype: Cells lacking this gene have morphologies and growth phenotypes similar to those of the wild-type strain. {ECO:0000269|PubMed:20305661}.

Annotations taken from UniProtKB at the EBI.


Organism:		Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
Taxonomy:		Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex.



Function:		Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems (By similarity). {ECO:0000250}.


Pathway:		Cell wall biogenesis; peptidoglycan biosynthesis.
Disruption phenotype:		Cells lacking this gene have morphologies and growth phenotypes similar to those of the wild-type strain. {ECO:0000269\|PubMed:20305661}.