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UniProt functional annotation for A0R5M9 | ||
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| UniProt code: A0R5M9. |
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| Organism: | |
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis). |
| Taxonomy: | |
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycolicibacterium. |
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| Function: | |
Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. {ECO:0000269|PubMed:20420449}. |
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| Catalytic activity: | |
Reaction=H2O + L-gamma-glutamyl-hercynylcysteine S-oxide = L-glutamate + S-(hercyn-2-yl)-L-cysteine S-oxide; Xref=Rhea:RHEA:42684, ChEBI:CHEBI:15377, ChEBI:CHEBI:29985, ChEBI:CHEBI:82703, ChEBI:CHEBI:82706; EC=3.5.1.118; Evidence={ECO:0000269|PubMed:20420449}; |
| Pathway: | |
Amino-acid biosynthesis; ergothioneine biosynthesis. {ECO:0000305|PubMed:20420449}. |
Annotations taken from UniProtKB at the EBI.