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UniProt functional annotation for Q05871 | ||
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| UniProt code: Q05871. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Essential for the beta oxidation of unsaturated fatty acids. {ECO:0000269|PubMed:9837886}. |
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| Catalytic activity: | |
Reaction=a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA; Xref=Rhea:RHEA:45900, ChEBI:CHEBI:85097, ChEBI:CHEBI:85489; EC=5.3.3.8; |
| Catalytic activity: | |
Reaction=a (3E)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA; Xref=Rhea:RHEA:45228, ChEBI:CHEBI:58521, ChEBI:CHEBI:85097; EC=5.3.3.8; |
| Pathway: | |
Lipid metabolism; fatty acid beta-oxidation. |
| Subunit: | |
Homohexamer, dimer of trimers. Interacts with DCI1. {ECO:0000269|PubMed:10381339, ECO:0000269|PubMed:10944342, ECO:0000269|PubMed:11399063, ECO:0000269|PubMed:14741345}. |
| Subcellular location: | |
Peroxisome {ECO:0000269|PubMed:10381339, ECO:0000269|PubMed:11302517, ECO:0000269|PubMed:9837886}. Note=This location is DCI1 dependent. |
| Induction: | |
By oleate. {ECO:0000269|PubMed:9837886}. |
| Similarity: | |
Belongs to the enoyl-CoA hydratase/isomerase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.