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UniProt functional annotation for Q97UL5 | ||
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| UniProt code: Q97UL5. |
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| Organism: | |
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus). |
| Taxonomy: | |
Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus. |
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| Function: | |
Catalyzes the decarboxylation of mevalonate 5-diphosphate (MVAPP) to isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. {ECO:0000269|PubMed:23378249}. |
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| Catalytic activity: | |
Reaction=(R)-5-diphosphomevalonate + ATP = ADP + CO2 + isopentenyl diphosphate + phosphate; Xref=Rhea:RHEA:23732, ChEBI:CHEBI:16526, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:57557, ChEBI:CHEBI:128769, ChEBI:CHEBI:456216; EC=4.1.1.33; Evidence={ECO:0000269|PubMed:23378249}; |
| Pathway: | |
Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 3/3. {ECO:0000269|PubMed:23378249}. |
| Subunit: | |
Homodimer. {ECO:0000250}. |
| Similarity: | |
Belongs to the diphosphomevalonate decarboxylase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.