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PDBsum entry 4yif
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DNA binding protein
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PDB id
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4yif
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References listed in PDB file
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Key reference
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Title
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Structure of the marr family protein rv0880 from mycobacterium tuberculosis.
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Authors
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Y.R.Gao,
N.Feng,
T.Chen,
D.E. .F.Li,
L.J.Bi.
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Ref.
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Acta Crystallogr F Struct Biol Commun, 2015,
71,
741-745.
[DOI no: ]
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PubMed id
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Abstract
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Rv0880 from the pathogen Mycobacterium tuberculosis is classified as a MarR
family protein in the Pfam database. It consists of 143 amino acids and has an
isoelectric point of 10.9. Crystals of Rv0880 belonged to space group P1, with
unit-cell parameters a = 54.97, b = 69.60, c = 70.32 Å, α = 103.71, β =
111.06, γ = 105.83°. The structure of the MarR family transcription regulator
Rv0880 was solved at a resolution of 2.0 Å with an R(cryst) and R(free) of 21.2
and 24.9%, respectively. The dimeric structure resembles that of other MarR
proteins, with each subunit comprising a winged helix-turn-helix domain
connected to an α-helical dimerization domain.
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