PDBsum entry 4xo1

Protein binding

PDB id: 4xo1

Contents

Protein chain

60 a.a.

Waters ×44

References listed in PDB file

Key reference

• Title: Crystal structure of gnsa from escherichia coli.
• Authors: Y.Wei, L.Zhan, Z.Gao, G.G.Privé, Y.Dong.
• Ref.: Biochem Biophys Res Commun, 2015, 462, 1-7. [DOI no: 10.1016/j.bbrc.2015.03.133]
• PubMed id: 25839658

Abstract

Escherichia Coli GnsA is a regulator of phosphatidylethanolamine synthesis and functions as a suppressor of both a secG null mutation and fabA6 mutations. GnsA may also be a toxin with the cognate antitoxin YmcE. Here we report the crystal structure of GnsA to 1.8 Å. GnsA forms a V shaped hairpin structure that is tightly associated into a homodimer. Our comprehensive structural study suggests that GnsA is structurally similar to an outer membrane protein, suggesting a function of protein binding.