|
|
||
|
|
|
|
|
UniProt functional annotation for P29295 | ||
|
|
|
|
|
|
||
| UniProt code: P29295. |
|
||
| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
|
||
|
||
| Function: | |
Associated with repair of damaged DNA and meiosis. Phosphorylates serine and threonine. Can use casein as a substrate. |
|
||
| Catalytic activity: | |
Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA- COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1; |
| Catalytic activity: | |
Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.1; |
| Subunit: | |
Interacts with HRI1. {ECO:0000269|PubMed:21460040}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:12628929}. Nucleus, nucleolus {ECO:0000269|PubMed:12628929}. Nucleus, nucleoplasm {ECO:0000269|PubMed:12628929}. |
| Miscellaneous: | |
Present with 10300 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.