UniProt functional annotation for P40090

UniProt code: P40090.

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
 
Function: Involved in sister chromatid cohesion (PubMed:10882066). Forms a complex with SCC2, which is required for the association of the cohesin complex with chromosomes (PubMed:10882066, PubMed:26038942). Binds to the nucleosome-free promoter regions of ribosomal protein genes and tRNA genes (PubMed:25173104). {ECO:0000269|PubMed:10882066, ECO:0000269|PubMed:25173104, ECO:0000269|PubMed:26038942}.
 
Subunit: Interacts with SCC2 to form the cohesin loading complex. {ECO:0000269|PubMed:10882066, ECO:0000269|PubMed:26038942}.
Subcellular location: Nucleus {ECO:0000269|PubMed:10882066, ECO:0000269|PubMed:25173104}. Note=Associates with chromatin. {ECO:0000269|PubMed:10882066, ECO:0000269|PubMed:25173104}.
Miscellaneous: Present with 907 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity: Belongs to the SCC4/mau-2 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.