UniProt functional annotation for P54651

UniProt code: P54651.

Organism: Dictyostelium discoideum (Slime mold).
Taxonomy: Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales; Dictyosteliaceae; Dictyostelium.
 
Function: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity). {ECO:0000250}.
 
Subunit: Homodimer. {ECO:0000250}.
Subcellular location: Cytoplasm {ECO:0000305}.
Domain: The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins. {ECO:0000250}.
Similarity: Belongs to the heat shock protein 90 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.