PDBsum entry 4x12

Viral protein

PDB id: 4x12

Contents

Protein chains

257 a.a.

Ligands

SIA-SIA ×3

GOL ×9

EDO ×18

Metals

__K ×10

Waters ×1034

PDB id:

4x12

Name:

Viral protein

Title:

Jc polyomavirus genotype 3 vp1 in complex with gd1b oligosaccharide

Structure:

Major capsid protein. Chain: a, b, c, d, e. Fragment: unp residues 23-290. Synonym: vp1,vp1 capsid protein. Engineered: yes

Source:

Jc polyomavirus type 3. Jcpyv. Organism_taxid: 804310. Gene: vp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.90Å R-factor: 0.160 R-free: 0.187

Authors:

L.J.Stroh,T.Stehle

Key ref:

L.J.Ströh et al. (2015). The Greater Affinity of JC Polyomavirus Capsid for α2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J Virol, 89, 6364-6375. PubMed id: 25855729 DOI: 10.1128/JVI.00489-15

Date:

24-Nov-14 Release date: 22-Apr-15

Protein chains

P90498  (P90498_POVJC) -  Capsid protein VP1 from JC polyomavirus

Seq: 354 a.a.

Struc: 257 a.a.

DOI no: 10.1128/JVI.00489-15

J Virol 89:6364-6375 (2015)

PubMed id: 25855729

The Greater Affinity of JC Polyomavirus Capsid for α2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.

L.J.Ströh, M.S.Maginnis, B.S.Blaum, C.D.Nelson, U.Neu, G.V.Gee, B.A.O'Hara, N.Motamedi, D.DiMaio, W.J.Atwood, T.Stehle.

ABSTRACT

No abstract given.