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UniProt functional annotation for E8T217 | ||
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| UniProt code: E8T217. |
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| Organism: | |
Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1). |
| Taxonomy: | |
Bacteria; Aquificae; Desulfurobacteriales; Desulfurobacteriaceae; Thermovibrio. |
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| Function: | |
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. {ECO:0000256|ARBA:ARBA00004065, ECO:0000256|RuleBase:RU003515}. |
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| Catalytic activity: | |
Reaction=Endonucleolytic cleavage to 5'-phosphomonoester.; EC=3.1.26.4; Evidence={ECO:0000256|ARBA:ARBA00000077, ECO:0000256|RuleBase:RU003515}; |
| Cofactor: | |
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|ARBA:ARBA00001946}; |
| Cofactor: | |
Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000256|ARBA:ARBA00001936}; |
| Similarity: | |
Belongs to the RNase HII family. {ECO:0000256|RuleBase:RU003515}. |
| Similarity: | |
Belongs to the RNase HII family. RnhC subfamily. {ECO:0000256|ARBA:ARBA00008378}. |
Annotations taken from UniProtKB at the EBI.