UniProt functional annotation for P0AG55

UniProt codes: P0AG55, P02390.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: This protein binds directly to at least 2 domains of the 23S ribosomal RNA, thus is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. {ECO:0000269|PubMed:6170935}.
 
Function: Gentamicin-resistant mutations in this protein affect translation fidelity. {ECO:0000269|PubMed:369594}.
 
Subunit: Part of the 50S ribosomal subunit (PubMed:324885, PubMed:10094780, PubMed:10756104, PubMed:12809609, PubMed:16272117, PubMed:25310980, PubMed:27906160, PubMed:27906161). {ECO:0000269|PubMed:10094780, ECO:0000269|PubMed:10756104, ECO:0000269|PubMed:12809609, ECO:0000269|PubMed:16272117, ECO:0000269|PubMed:24844575, ECO:0000269|PubMed:25310980, ECO:0000269|PubMed:27906160, ECO:0000269|PubMed:27906161, ECO:0000269|PubMed:27934701, ECO:0000269|PubMed:324885}.
Mass spectrometry: Mass=18772.7; Method=MALDI; Evidence={ECO:0000269|PubMed:10094780};
Similarity: Belongs to the universal ribosomal protein uL6 family. {ECO:0000255|HAMAP-Rule:MF_01365}.

Annotations taken from UniProtKB at the EBI.