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UniProt functional annotation for Q00511 | ||
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| UniProt code: Q00511. |
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| Organism: | |
Aspergillus flavus. |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus subgen. Circumdati. |
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| Function: | |
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. |
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| Catalytic activity: | |
Reaction=H2O + O2 + urate = 5-hydroxyisourate + H2O2; Xref=Rhea:RHEA:21368, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240, ChEBI:CHEBI:17775, ChEBI:CHEBI:18072; EC=1.7.3.3; |
| Pathway: | |
Purine metabolism; urate degradation; (S)-allantoin from urate: step 1/3. |
| Subunit: | |
Homotetramer. {ECO:0000269|PubMed:9360612}. |
| Subcellular location: | |
Peroxisome. |
| Similarity: | |
Belongs to the uricase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.