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UniProt functional annotation for Q9PPB4 | ||
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| UniProt code: Q9PPB4. |
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| Organism: | |
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168). |
| Taxonomy: | |
Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Campylobacteraceae; Campylobacter. |
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| Function: | |
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). {ECO:0000255|HAMAP-Rule:MF_00418}. |
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| Catalytic activity: | |
Reaction=L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy- 2,3,4,5-tetrahydrodipicolinate + H(+) + H2O; Xref=Rhea:RHEA:34171, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:67139, ChEBI:CHEBI:537519; EC=4.3.3.7; Evidence={ECO:0000255|HAMAP-Rule:MF_00418}; |
| Pathway: | |
Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4. {ECO:0000255|HAMAP-Rule:MF_00418}. |
| Subunit: | |
Homotetramer; dimer of dimers. {ECO:0000255|HAMAP- Rule:MF_00418}. |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00418}. |
| Similarity: | |
Belongs to the DapA family. {ECO:0000255|HAMAP- Rule:MF_00418}. |
Annotations taken from UniProtKB at the EBI.