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UniProt functional annotation for O75319 | ||
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| UniProt code: O75319. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro). Binds to RNA. May participate in nuclear mRNA metabolism. {ECO:0000269|PubMed:10347225, ECO:0000269|PubMed:24447265, ECO:0000269|PubMed:9685386}. |
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| Subunit: | |
Monomer (PubMed:24531476). May interact with SFRS7 and SFRS9/SRP30C (PubMed:24447265). {ECO:0000269|PubMed:24447265, ECO:0000269|PubMed:24531476}. |
| Subcellular location: | |
Nucleus {ECO:0000269|PubMed:9685386}. Nucleus speckle {ECO:0000269|PubMed:9685386}. |
| Similarity: | |
Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. {ECO:0000305}. |
| Sequence caution: | |
Sequence=AAC39925.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=AAH00346.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAG37685.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.