UniProt functional annotation for P76141

UniProt code: P76141.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes. {ECO:0000269|PubMed:15601708, ECO:0000269|PubMed:15743955, ECO:0000269|PubMed:17557827}.
 
Subcellular location: Cytoplasm {ECO:0000305}.
Induction: Autoregulated.
Similarity: Belongs to the SorC transcriptional regulatory family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.