UniProt functional annotation for O32080

UniProt code: O32080.

Organism: Bacillus subtilis (strain 168).
Taxonomy: Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
 
Function: Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress. {ECO:0000269|PubMed:12562800}.
 
Subunit: Homodimer, tetramer (dimer of homodimer) and octamer (tetramer of homodimer). Part of the KtrAB complex formed by an octameric catalytic ring of KtrA and a membrane associated dimer of KtrB forming a potassium channel. {ECO:0000269|PubMed:12086676, ECO:0000269|PubMed:16990138}.
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Disruption phenotype: Impaired potassium uptake. {ECO:0000269|PubMed:12562800}.
Similarity: Belongs to the KtrA potassium transport family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.