 |
PDBsum entry 4j4q
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Signaling protein
|
PDB id
|
|
|
|
4j4q
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
References listed in PDB file
|
|
|
Key reference
|
|
|
Title
|
|
Opsin, A structural model for olfactory receptors?
|
|
|
Authors
|
|
J.H.Park,
T.Morizumi,
Y.Li,
J.E.Hong,
E.F.Pai,
K.P.Hofmann,
H.W.Choe,
O.P.Ernst.
|
|
|
Ref.
|
|
Angew Chem Int Ed Engl, 2013,
52,
11021-11024.
[DOI no: ]
|
|
|
PubMed id
|
|
|
|
|
|
Abstract
|
|
|
Receptor-ligand interaction: Olfactory receptors (ORs) are G-protein-coupled
receptors (GPCRs), which detect signaling molecules such as hormones and
odorants. The structure of opsin, the GPCR employed in vision, with a detergent
molecule bound deep in its orthosteric ligand-binding pocket provides a template
for OR homology modeling, thus enabling investigation of the structural basis of
the mechanism of odorant-receptor recognition.
|
|
|
|
|
|
|
