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UniProt functional annotation for B4EA21 | ||
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| UniProt code: B4EA21. |
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| Organism: | |
Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)). |
| Taxonomy: | |
Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; Burkholderia cepacia complex. |
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| Function: | |
Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). {ECO:0000256|HAMAP-Rule:MF_01929, ECO:0000256|PIRNR:PIRNR001338}. |
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| Catalytic activity: | |
Reaction=5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5- amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate; Xref=Rhea:RHEA:13193, ChEBI:CHEBI:15378, ChEBI:CHEBI:58730, ChEBI:CHEBI:77657; EC=5.4.99.18; Evidence={ECO:0000256|HAMAP- Rule:MF_01929, ECO:0000256|PIRNR:PIRNR001338}; |
| Pathway: | |
Purine metabolism; IMP biosynthesis via de novo pathway; 5- amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5- phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2. {ECO:0000256|HAMAP-Rule:MF_01929, ECO:0000256|PIRNR:PIRNR001338}. |
| Similarity: | |
Belongs to the AIR carboxylase family. {ECO:0000256|PIRNR:PIRNR001338}. |
| Similarity: | |
Belongs to the AIR carboxylase family. Class I subfamily. {ECO:0000256|HAMAP-Rule:MF_01929}. |
Annotations taken from UniProtKB at the EBI.