PDBsum entry 4gio

Unknown function

PDB id: 4gio

Contents

Protein chains

96 a.a.

Metals

_BR ×3

Waters ×133

References listed in PDB file

Key reference

• Title: Crystal structure of the campylobacter jejuni cj0090 protein reveals a novel variant of the immunoglobulin fold among bacterial lipoproteins.
• Authors: S.Paek, F.Kawai, K.J.Choi, H.J.Yeo.
• Ref.: Proteins, 2012, 80, 2804-2809.
• PubMed id: 22987763

Abstract

Bacterial lipoproteins play an important role in bacterial pathogenesis and physiology. The genome of Campylobacter jejuni, a major foodborn pathogen, is predicted to contain over 20 lipoproteins. However, the functions of the majority of C. jejuni lipoproteins remain unknown. The Cj0090 protein is encoded by a lipoprotein operon composed of cj0089, cj0090, and cj0091. Here, we report the crystal structure of Cj0090 at 1.9 Å resolution, revealing a novel variant of the immunoglobulin fold with β-sandwich architecture. The structure suggests that Cj0090 may be involved in protein-protein interactions, consistent with a possible role for bacterial lipoproteins. Proteins 2012;. © 2012 Wiley Periodicals, Inc.