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UniProt functional annotation for I3PA93 | ||
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| UniProt code: I3PA93. |
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| Organism: | |
Cajanus cajan (Pigeon pea) (Cajanus indicus). |
| Taxonomy: | |
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade; NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Cajanus. |
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| Catalytic activity: | |
Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+); Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938; EC=3.5.1.5; Evidence={ECO:0000256|ARBA:ARBA00000242, ECO:0000256|PIRNR:PIRNR001222}; |
| Cofactor: | |
Name=Ni cation; Xref=ChEBI:CHEBI:25516; Evidence={ECO:0000256|ARBA:ARBA00001948}; |
| Cofactor: | |
Name=Ni cation; Xref=ChEBI:CHEBI:25516; Evidence={ECO:0000256|PIRNR:PIRNR001222, ECO:0000256|PIRSR:PIRSR001222-51}; Note=Binds 2 nickel ions per subunit. {ECO:0000256|PIRNR:PIRNR001222, ECO:0000256|PIRSR:PIRSR001222-51}; |
| Pathway: | |
Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}. |
| Pathway: | |
Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. {ECO:0000256|ARBA:ARBA00004897, ECO:0000256|PIRNR:PIRNR001222}. |
| Subunit: | |
Homohexamer. {ECO:0000256|ARBA:ARBA00011643}. |
| Ptm: | |
Carbamylation allows a single lysine to coordinate two nickel ions. {ECO:0000256|PIRSR:PIRSR001222-50}. |
| Similarity: | |
In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. {ECO:0000256|ARBA:ARBA00007966, ECO:0000256|PIRNR:PIRNR001222}. |
Annotations taken from UniProtKB at the EBI.