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UniProt functional annotation for P22619 | ||
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| UniProt code: P22619. |
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| Organism: | |
Paracoccus denitrificans. |
| Taxonomy: | |
Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales; Rhodobacteraceae; Paracoccus. |
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| Function: | |
Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. |
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| Catalytic activity: | |
Reaction=H2O + methylamine + 2 oxidized [amicyanin] = formaldehyde + 2 H(+) + NH4(+) + 2 reduced [amicyanin]; Xref=Rhea:RHEA:30207, Rhea:RHEA-COMP:11100, Rhea:RHEA-COMP:11101, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16842, ChEBI:CHEBI:28938, ChEBI:CHEBI:29036, ChEBI:CHEBI:49552, ChEBI:CHEBI:59338; EC=1.4.9.1; |
| Cofactor: | |
Name=tryptophan tryptophylquinone residue; Xref=ChEBI:CHEBI:20251; Note=Uses a protein-derived tryptophan tryptophylquinone (TTQ) cofactor.; |
| Pathway: | |
One-carbon metabolism; methylamine degradation; formaldehyde from methylamine: step 1/1. |
| Subunit: | |
Heterotetramer of two light and two heavy chains. {ECO:0000269|PubMed:1599920}. |
| Subcellular location: | |
Periplasm. |
| Ptm: | |
Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. |
| Ptm: | |
Tryptophan tryptophylquinone (TTQ) is formed by oxidation of the indole ring of a tryptophan to form tryptophylquinone followed by covalent cross-linking with another tryptophan residue. |
| Similarity: | |
Belongs to the aromatic amine dehydrogenase light chain family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.