Crystal structure of a hmg domain of transcription factor sox-9 bound to DNA (sox-9/DNA) from homo sapiens at 2.77 a resolution
Structure:
Transcription factor sox-9. Chain: a. Fragment: hmg box containing residues 98-181. Engineered: yes. DNA (5'-d( Cp Tp Cp Tp Tp Tp Gp Ap Gp Ap Ap G)-3'). Chain: b. Engineered: yes. DNA (5'-d( Cp Tp Tp Cp Tp Cp Ap Ap Ap Gp Ap G)-3'). Chain: c.
Source:
Homo sapiens. Human. Organism_taxid: 9606. Gene: sgt82680, sox9. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: sequence matching the sox-9 binding site from the anti-mullerian hormone (amh) promoter, top strand.
Resolution:
2.77Å
R-factor:
0.248
R-free:
0.278
Authors:
Joint Center For Structural Genomics (Jcsg),Partnership For Stem Cell Biology (Stemcell)
Key ref:
Joint center for structural genomics (jcsg)
and
partnership for stem cell biology
Crystal structure of a hmg domain of transcription fa sox-9 bound to DNA (sox-9/DNA) from homo sapiens at 2 resolution.
To be published,
.
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