|
|
||
|
|
|
|
|
UniProt functional annotation for C0LT34 | ||
|
|
|
|
|
|
||
| UniProt code: C0LT34. |
|
||
| Organism: | |
Influenza B virus (B/Brisbane/60/2008). |
| Taxonomy: | |
Viruses; Riboviria; Orthornavirae; Negarnaviricota; Polyploviricotina; Insthoviricetes; Articulavirales; Orthomyxoviridae; Betainfluenzavirus. |
|
||
|
||
| Function: | |
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. {ECO:0000256|RuleBase:RU361252}. |
|
||
| Catalytic activity: | |
Reaction=Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha- (2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.; EC=3.2.1.18; Evidence={ECO:0000256|RuleBase:RU361252}; |
| Cofactor: | |
Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000256|ARBA:ARBA00001913, ECO:0000256|RuleBase:RU361252}; |
| Subunit: | |
Homotetramer. {ECO:0000256|ARBA:ARBA00011881, ECO:0000256|RuleBase:RU361252}. |
| Subcellular location: | |
Membrane {ECO:0000256|ARBA:ARBA00004606}; Single- pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}. Virion membrane {ECO:0000256|RuleBase:RU361252}. Host apical cell membrane {ECO:0000256|RuleBase:RU361252}; Single-pass type II membrane protein {ECO:0000256|RuleBase:RU361252}. |
| Ptm: | |
N-glycosylated. {ECO:0000256|RuleBase:RU361252}. |
| Similarity: | |
Belongs to the glycosyl hydrolase 34 family. {ECO:0000256|RuleBase:RU361252}. |
Annotations taken from UniProtKB at the EBI.