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UniProt functional annotation for P39045 | ||
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| UniProt code: P39045. |
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| Organism: | |
Actinomadura sp. (strain R39). |
| Taxonomy: | |
Bacteria; Actinobacteria; Streptosporangiales; Thermomonosporaceae; Actinomadura; unclassified Actinomadura. |
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| Function: | |
Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. |
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| Catalytic activity: | |
Reaction=Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are N-acyl substituents of D-alanine.; EC=3.4.16.4; |
| Activity regulation: | |
Inhibited by benzylpenicillin, cephaloridine, ampicillin and cetiofur. {ECO:0000269|PubMed:11160090}. |
| Pathway: | |
Cell wall biogenesis; peptidoglycan biosynthesis. |
| Subcellular location: | |
Secreted. |
| Similarity: | |
Belongs to the peptidase S13 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.