 |
PDBsum entry 4al2
|
|
|
|
References listed in PDB file
|
 |
|
Key reference
|
|
|
Title
|
|
A fret enzyme-Based probe for monitoring hydrogen sulfide.
|
|
|
Authors
|
|
M.Strianese,
G.J.Palm,
S.Milione,
O.Kühl,
W.Hinrichs,
C.Pellecchia.
|
|
|
Ref.
|
|
Inorg Chem, 2012,
51,
11220-11222.
|
|
|
PubMed id
|
|
|
|
|
|
Abstract
|
|
|
Fluorescently labeled cobalt peptide deformylase (Co-PDF) can be efficiently
used as a fluorescence-resonance-energy-transfer-based sensing device for
hydrogen sulfide (H(2)S). The proof of concept of our sensor system is
substantiated by spectroscopic, structural, and theoretical results.
Monohydrogen sulfide coordination to Co-PDF and Ni-PDF was verified by X-ray
crystallography. Density functional theory calculations were performed to gain
insight into the characteristics of the coordination adduct between H(2)S and
the cobalt cofactor in Co-PDF.
|
|
|
|
|
|
|
