UniProt functional annotation for B6K9M7

UniProt code: B6K9M7.

Organism: Toxoplasma gondii (strain ATCC 50861 / VEG).
Taxonomy: Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia; Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
 
Function: May play a role in host cell invasion. {ECO:0000250}.
 
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000305}. Secreted {ECO:0000250}. Note=Initially localizes to micronemes, specialized secretory organelles of apicomplexan parasites important for host cell invasion. Relocalizes to the surface membrane upon host invasion. {ECO:0000250}.
Induction: Readily detected in oocysts (at protein level). Specifically up-regulated in sporozoites, but not in tachyzoites and bradyzoites. {ECO:0000269|PubMed:22279555, ECO:0000269|PubMed:22347997}.
Ptm: Proteolytically cleaved within its transmembrane domain, releasing a soluble form from the cell surface. {ECO:0000250}.
Similarity: Belongs to the apicomplexan parasites AMA1 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.