UniProt functional annotation for P13574

UniProt code: P13574.

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
 
Function: Binds to the DNA sequence mediating pheromone induction (called the pheromone response element = PRE) which is found in the upstream control region of several a-, alpha- and haploid-specific genes. Involved in mating of haploids and in pseudohyphae formation in diploids.
 
Subunit: Interacts with mating-type protein ALPHA1. {ECO:0000269|PubMed:8339934}.
Subcellular location: Nucleus.
Domain: The DNA-binding domain seems to be involved in the suppression of pseudohyphae formation under nitrogen-rich conditions and in haploids. This region is also involved in the regulation of budding pattern of haploids.
Ptm: Phosphorylated by the STE7, STE11 and STE20 kinases.
Miscellaneous: Present with 1920 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity: Belongs to the STE12 transcription factor family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.