UniProt functional annotation for P23395

UniProt code: P23395.

Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
Taxonomy: Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
 
Function: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
Catalytic activity: Reaction=ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L- methionyl-tRNA(Met); Xref=Rhea:RHEA:13481, Rhea:RHEA-COMP:9667, Rhea:RHEA-COMP:9698, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57844, ChEBI:CHEBI:78442, ChEBI:CHEBI:78530, ChEBI:CHEBI:456215; EC=6.1.1.10;
Cofactor: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.;
Subunit: Homodimer.
Subcellular location: Cytoplasm.
Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.