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UniProt functional annotation for P0A029 | ||
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| UniProt code: P0A029. |
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| Organism: | |
Staphylococcus aureus (strain Mu50 / ATCC 700699). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus. |
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| Function: | |
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. {ECO:0000255|HAMAP-Rule:MF_00909}. |
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| Activity regulation: | |
Calcium ions inhibit the GTPase activity and promote the polymerization of FtsZ. {ECO:0000269|PubMed:22948918}. |
| Subunit: | |
Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. {ECO:0000255|HAMAP-Rule:MF_00909}. |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00909}. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane. {ECO:0000255|HAMAP-Rule:MF_00909}. |
| Similarity: | |
Belongs to the FtsZ family. {ECO:0000255|HAMAP- Rule:MF_00909}. |
Annotations taken from UniProtKB at the EBI.