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UniProt functional annotation for P38348 | ||
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| UniProt code: P38348. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Involved in DNA mismatch repair in slow-growing cells. Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC). {ECO:0000269|PubMed:10681182, ECO:0000269|PubMed:10681183, ECO:0000269|PubMed:15450405, ECO:0000269|PubMed:19217412, ECO:0000269|PubMed:19412159, ECO:0000269|PubMed:19446322, ECO:0000269|PubMed:9539417}. |
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| Subunit: | |
Interacts with RPT1, RPT2, RPT3, RPT5, RPT6, RPN1 and RPN2. Part of transient complex (BP1) containing HSM3, RPT1, RPT2 and RPT5 formed during the assembly of the 26S proteasome. {ECO:0000269|PubMed:19217412, ECO:0000269|PubMed:19412159, ECO:0000269|PubMed:19412160}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:14562095}. |
| Miscellaneous: | |
Present with 468 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the proteasome subunit S5B/HSM3 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.