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UniProt functional annotation for P43629 | ||
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| UniProt code: P43629. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis. {ECO:0000269|PubMed:22020283}. |
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| Subcellular location: | |
Cell membrane; Single-pass type I membrane protein. |
| Domain: | |
Ig-like C2-type domain 2 mediates specificity through recognition of the Bw4 epitope. {ECO:0000269|PubMed:22020283}. |
| Similarity: | |
Belongs to the immunoglobulin superfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.