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UniProt functional annotation for Q99ZV9 | ||
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| UniProt code: Q99ZV9. |
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| Organism: | |
Streptococcus pyogenes serotype M1. |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus. |
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| Function: | |
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity). Binds dsDNA, binding is disrupted by EGTA. {ECO:0000250}. |
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| Cofactor: | |
Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000269|PubMed:22479393}; Note=Binds up to 2 Ca(2+) per subunit. {ECO:0000269|PubMed:22479393}; |
| Subunit: | |
Homotetramer. Binds dsDNA. {ECO:0000269|PubMed:22479393}. |
| Similarity: | |
Belongs to the CRISPR-associated Csn2 protein family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.