PDBsum entry 3uz3 Go to PDB code:  Tunnel analysis for: 3uz3 calculated with MOLE 2.0 PDB id 3uz3 Tunnels calculated on whole structure Tunnels calculated excluding ligands View options MOLEonline 2.0 manipulation and visualization with HETATM: without HETATM:   16 tunnels, coloured by tunnel radius 22 tunnels, coloured by tunnel radius 22 tunnels, coloured as in list below Tunnels are interior spaces connected with the protein surrounding. Only channels longer than 15 Å are shown. Tunnels Free R Length HPathy HPhob Polar Rel Mut Residue..type Ligands Radius 1 1.32 1.32 56.6 -0.81 -0.79 8.7 84 1 1 0 0 0 0 0  U 45 A G 57 A A 60 A G 61 A U 62 A G 111 A G 112 A C 308 A G 309 A C 355 A A 356 A U 368 A C 369 A C 370 A G 371 A G 376 A G 377 A G 378 A C 379 A G 388 A A 389 A C 390 A G 391 A G 392 A A 393 A MG 1953 A MG 2020 A MG 2278 A 2 1.34 1.34 64.6 -0.95 -0.77 10.6 80 2 1 0 0 0 0 0  C 40 A G 41 A G 42 A C 43 A U 45 A A 60 A G 61 A U 62 A G 111 A G 112 A C 308 A G 309 A G 376 A G 377 A G 378 A C 379 A A 389 A C 390 A G 391 A G 392 A A 393 A G 394 A C 395 A G 396 A MG 1953 A MG 2278 A MG 2280 A MG 2281 A 3 1.36 1.36 64.6 -0.83 -0.68 7.6 85 2 0 1 1 0 0 0  A 60 A G 61 A U 62 A G 107 A G 108 A C 110 A G 111 A A 134 A C 135 A C 136 A C 137 A G 138 A G 139 A C 218 A C 219 A G 220 A G 376 A G 377 A G 378 A C 379 A G 380 A A 382 A A 465 A G 467 A MG 2173 A 4 1.32 1.32 64.7 -0.70 -0.79 7.3 84 1 1 0 0 0 0 0  U 45 A G 46 A C 47 A A 60 A G 61 A U 62 A G 111 A G 112 A G 113 A U 114 A C 308 A G 309 A C 355 A A 356 A G 357 A U 358 A U 359 A G 362 A U 365 A C 366 A G 376 A G 377 A G 378 A C 379 A A 389 A C 390 A G 391 A MG 1951 A MG 1952 A MG 1953 A MG 1954 A MG 1955 A MG 2282 A 5 1.31 1.31 65.8 -0.94 -0.69 11.7 88 2 1 0 1 0 0 0  A 60 A G 61 A U 62 A G 107 A G 108 A C 110 A G 111 A A 134 A C 135 A C 372 A A 373 A A 374 A G 376 A G 377 A G 378 A C 379 A G 380 A G 384 A C 385 A U 480 A MG 1938 A MG 1972 A MG 2173 A 6 1.33 1.33 65.5 -0.66 -0.78 6.4 83 1 0 0 0 0 0 0  A 60 A G 61 A U 62 A G 108 A A 109 A C 110 A G 111 A G 122 A C 123 A G 124 A U 125 A G 127 A G 230 A G 231 A G 232 A C 233 A C 234 A C 312 A A 313 A G 326 A C 328 A G 376 A G 377 A G 378 A C 379 A MG 2087 A 7 1.32 1.32 75.8 -0.73 -0.78 7.1 94 2 0 1 0 0 0 0  A 60 A G 61 A U 62 A C 106 A G 107 A G 108 A C 110 A G 111 A A 134 A C 135 A G 146 A G 147 A A 172 A U 173 A C 174 A C 175 A C 176 A A 196 A A 197 A G 198 A U 222 A A 325 A G 376 A G 377 A G 378 A C 379 A MG 1693 A 8 1.31 1.31 78.6 -0.85 -0.73 8.3 87 3 0 1 0 0 0 0  A 60 A G 61 A U 62 A C 106 A G 107 A G 108 A C 110 A G 111 A C 132 A U 133 A A 134 A C 135 A A 185 A G 191 A i:B G 191 A i:C U 222 A U 223 A C 224 A C 225 A G 226 A A 325 A G 376 A G 377 A G 378 A C 379 A 9 1.33 1.33 80.5 -0.62 -0.78 5.9 83 1 0 0 0 0 0 0  A 60 A G 61 A U 62 A G 108 A A 109 A C 110 A G 111 A G 230 A G 231 A G 232 A C 233 A G 260 A A 263 A G 265 A C 267 A C 268 A C 269 A A 270 A C 312 A A 313 A A 321 A G 326 A C 328 A G 376 A G 377 A G 378 A C 379 A U 1436 A C 1437 A G 1438 A G 1464 A C 1465 A MG 2087 A 10 1.33 1.33 85.5 -0.56 -0.79 5.3 83 1 0 0 0 0 0 0  A 60 A G 61 A U 62 A G 108 A A 109 A C 110 A G 111 A U 118 A A 119 A A 120 A G 230 A G 231 A G 232 A C 233 A G 251 A U 252 A C 267 A C 268 A C 312 A A 313 A C 314 A G 319 A C 320 A G 326 A C 328 A G 376 A G 377 A G 378 A C 379 A C 1426 A U 1427 A A 1428 A C 1429 A G 1467 A A 1468 A MG 2087 A 11 1.32 1.32 86.7 -0.84 -0.74 8.9 74 3 1 0 0 1 0 0  G 31 A U 45 A G 46 A C 47 A C 48 A U 49 A A 60 A G 61 A U 62 A G 111 A G 112 A G 113 A U 114 A G 115 A G 286 A U 287 A A 288 A G 289 A U 304 A G 305 A G 306 A C 307 A C 308 A G 309 A C 355 A A 356 A G 376 A G 377 A G 378 A C 379 A A 389 A C 390 A G 391 A C 1479 A MG 1951 A MG 1952 A MG 1953 A MG 2065 A MG 2279 A 12 1.32 1.32 87.1 -0.74 -0.79 8.0 79 2 2 0 0 0 0 0  U 5 A G 6 A G 29 A U 30 A U 45 A A 60 A G 61 A U 62 A G 111 A G 112 A C 295 A U 296 A G 297 A G 299 A G 306 A C 307 A C 308 A G 309 A G 376 A G 377 A G 378 A C 379 A A 389 A C 390 A G 391 A C 400 A G 610 A A 611 A C 612 A C 623 A C 624 A G 629 A G 630 A G 631 A MG 1940 A MG 2231 A 13 1.36 1.36 90.6 -0.75 -0.77 7.5 88 3 0 1 0 0 0 0  A 60 A G 61 A U 62 A C 106 A G 107 A G 108 A C 110 A G 111 A A 134 A C 135 A C 175 A C 176 A C 177 A C 178 A A 179 A U 180 A G 181 A G 191 A U 192 A C 193 A C 194 A A 195 A A 196 A A 197 A U 222 A A 325 A G 376 A G 377 A G 378 A C 379 A MG 1693 A MG 2342 A 14 1.36 1.36 91.7 -1.01 -0.78 10.7 79 4 3 1 0 1 0 0  G 29 A U 30 A U 45 A A 60 A G 61 A U 62 A G 111 A G 112 A C 295 A G 306 A C 307 A C 308 A G 309 A G 376 A G 377 A G 378 A C 379 A A 389 A C 390 A G 391 A C 400 A G 610 A C 612 A C 613 A A 614 A C 615 A G 616 A G 617 A C 620 A A 621 A A 622 A C 623 A C 624 A 15 1.36 1.36 94.0 -0.60 -0.78 5.8 83 1 0 0 0 0 0 0  A 60 A G 61 A U 62 A G 108 A A 109 A C 110 A G 111 A G 230 A G 231 A G 232 A C 233 A C 312 A A 313 A C 314 A A 315 A G 316 A G 319 A C 320 A G 326 A C 328 A A 329 A G 331 A G 333 A C 334 A C 335 A C 336 A C 337 A G 348 A A 349 A G 350 A G 351 A G 376 A G 377 A G 378 A C 379 A MG 2087 A MG 2226 A 16 1.34 1.34 96.5 -0.96 -0.75 10.0 85 5 0 1 0 0 0 0  A 60 A G 61 A U 62 A G 108 A A 109 A C 110 A G 111 A G 230 A G 231 A G 232 A U 261 A A 262 A A 263 A C 322 A U 323 A G 324 A G 326 A A 327 A C 328 A G 376 A G 377 A G 378 A C 379 A C 1437 A G 1438 A C 1439 A C 1440 A G 1441 A G 1442 A G 1453 A G 1454 A MG 2087 A MG 2119 A MG 2326 A 17 1.34 1.34 131.9 -0.95 -0.78 9.3 85 6 3 2 0 0 0 0  A 26 A G 27 A G 28 A G 29 A U 30 A U 45 A A 60 A G 61 A U 62 A G 111 A G 112 A C 295 A G 306 A C 307 A C 308 A G 309 A G 376 A G 377 A G 378 A C 379 A A 389 A C 390 A G 391 A C 400 A G 500 A C 501 A C 503 A C 504 A C 508 A A 509 A C 522 A A 523 A G 524 A C 536 A G 537 A A 539 A G 540 A G 541 A G 542 A C 549 A G 550 A U 551 A G 610 A C 612 A C 623 A C 624 A MG 1907 A MG 1908 A MG 1909 A MG 2071 A MG 2246 A MG 2254 A 18 1.33 1.37 136.6 -1.11 -0.68 11.2 81 9 2 1 0 1 0 0  C 25 A A 26 A G 27 A G 28 A G 29 A U 30 A U 45 A A 60 A G 61 A U 62 A G 111 A G 112 A C 295 A G 306 A C 307 A C 308 A G 309 A G 376 A G 377 A G 378 A C 379 A A 389 A C 390 A G 391 A C 400 A A 520 A G 521 A C 522 A A 523 A G 524 A C 549 A G 550 A U 551 A U 552 A C 554 A G 610 A C 612 A C 623 A C 624 A MG 1909 A MG 2178 A 19 1.34 1.34 153.7 -1.21 -0.62 13.4 83 10 4 5 5 1 1 0  A 8 A G 9 A A 10 A A 26 A G 27 A G 28 A G 29 A U 30 A U 45 A A 60 A G 61 A U 62 A G 111 A G 112 A C 295 A G 306 A C 307 A C 308 A G 309 A G 376 A G 377 A G 378 A C 379 A A 389 A C 390 A G 391 A C 400 A G 506 A C 507 A C 508 A A 509 A G 544 A C 545 A C 549 A G 550 A G 610 A C 612 A C 623 A C 624 A MG 1907 A MG 1908 A 20 1.34 1.34 190.6 -0.84 -0.73 8.7 83 6 4 1 2 1 0 0  G 18 1 U 19 1 U 20 1 U 21 1 U 22 1 A 8 A G 9 A A 10 A G 11 A U 12 A U 13 A U 14 A G 15 A A 16 A A 26 A G 27 A G 28 A G 29 A U 30 A U 45 A A 60 A G 61 A U 62 A G 111 A G 112 A C 295 A G 306 A C 307 A C 308 A G 309 A G 376 A G 377 A G 378 A C 379 A A 389 A C 390 A G 391 A C 400 A G 506 A C 507 A C 508 A A 509 A G 527 A C 528 A G 544 A C 545 A C 549 A G 550 A G 610 A C 612 A C 623 A C 624 A A 913 A A 914 A A 915 A C 1403 A C 1404 A G 1491 A A 1492 A A 1493 A G 1494 A U 1495 A C 1496 A MG 1902 A MG 1907 A MG 1908 A PAR 2412 A U 39 B G 40 B U 28 C U 37 C 21 1.16 1.64 18.4 0.94 0.39 6.2 89 1 1 0 5 1 0 0  G 685 A 22 1.16 1.64 19.5 1.01 0.39 5.5 91 1 1 0 5 1 0 0  G 685 A Residue-type_colouring Positive Negative Neutral Aliphatic Aromatic Pro & Gly Cysteine H,K,R D,E S,T,N,Q A,V,L,I,M F,Y,W P,G C Acknowledgement Tunnels were calculated by MOLE 2.0 program version 2.5.13.11.08 and visualized using Pymol 0.97rc.