PDBsum entry 3u2b

Transcription/DNA

PDB id: 3u2b

Contents

Protein chain

76 a.a.

DNA/RNA

Waters ×8

PDB id:

3u2b

Name:

Transcription/DNA

Title:

Structure of the sox4 hmg domain bound to DNA

Structure:

DNA (5'-d( Gp Tp Cp Tp Cp Tp Ap Tp Tp Gp Tp Cp Cp Tp Gp G)- 3'). Chain: a. Engineered: yes. Other_details: sequence derived from the lama1 gene. DNA (5'-d( Cp Cp Ap Gp Gp Ap Cp Ap Ap Tp Ap Gp Ap Gp Ap C)- 3'). Chain: b. Engineered: yes.

Source:

Synthetic: yes. Other_details: synthetic DNA. Mus musculus. Mouse. Organism_taxid: 10090. Gene: sox4, sox-4. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.40Å R-factor: 0.238 R-free: 0.280

Authors:

R.Jauch,C.K.L.Ng,P.R.Kolatkar

Key ref:

R.Jauch et al. (2012). The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism for positional interdependence in DNA recognition. Biochem J, 443, 39-47. PubMed id: 22181698

Date:

03-Oct-11 Release date: 28-Dec-11

Protein chain

Q06831  (SOX4_MOUSE) -  Transcription factor SOX-4 from Mus musculus

Seq: 440 a.a.

Struc: 76 a.a.

DNA/RNA chains

G-T-C-T-C-T-A-T-T-G-T-C-C-T-G-G 16 bases

C-C-A-G-G-A-C-A-A-T-A-G-A-G-A-C 16 bases

Enzyme reactions

• Enzyme class: E.C.?

Biochem J 443:39-47 (2012)

PubMed id: 22181698

The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism for positional interdependence in DNA recognition.

R.Jauch, C.K.Ng, K.Narasimhan, P.R.Kolatkar.

ABSTRACT

No abstract given.