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UniProt functional annotation for Q9I6J0 | ||
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| UniProt code: Q9I6J0. |
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| Organism: | |
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas. |
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| Function: | |
Spermidine-binding protein probably required for its uptake into cells. Binds spermidine with high affinity (KD=14.3 nM). Does not bind putrescine, cadaverine or spermine. Spermidine binding induces large inter-domain conformational changes. Implicated in induction of type 3 secretion systems (T3SS), which play a role in virulence. {ECO:0000269|PubMed:22300763}. |
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| Subcellular location: | |
Periplasm {ECO:0000255|PIRNR:PIRNR019574}. |
| Disruption phenotype: | |
Significant decrease in T3SS induction. {ECO:0000269|PubMed:22300763}. |
| Similarity: | |
Belongs to the bacterial solute-binding protein PotD/PotF family. {ECO:0000255|PIRNR:PIRNR019574}. |
Annotations taken from UniProtKB at the EBI.