PDBsum entry 3t8h

Hydrolase/hydrolase inhibitor

PDB id: 3t8h

Contents

Protein chain

316 a.a.

Ligands

UBS

DMS ×5

GOL ×3

Metals

_CA ×4

_ZN

Waters ×446

PDB id:

3t8h

Name:

Hydrolase/hydrolase inhibitor

Title:

Thermolysin in complex with ubtln29

Structure:

Thermolysin. Chain: a. Fragment: mature form (unp residues 233-548). Synonym: thermostable neutral proteinase. Ec: 3.4.24.27

Source:

Bacillus thermoproteolyticus. Organism_taxid: 1427

Resolution:

1.45Å R-factor: 0.124 R-free: 0.153

Authors:

A.Biela,A.Heine,G.Klebe

Key ref:

A.Biela et al. Thermolysin inhibition. To be published, .

Date:

01-Aug-11 Release date: 01-Aug-12

Protein chain

P00800  (THER_BACTH) -  Thermolysin from Bacillus thermoproteolyticus

Seq: 548 a.a.

Struc: 316 a.a.

Enzyme reactions

• Enzyme class: E.C.3.4.24.27 - thermolysin.
• Reaction: Preferential cleavage: Xaa-|-Leu > Xaa-|-Phe.
• Cofactor: Ca(2+); Zn(2+)