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UniProt functional annotation for P0A881 | ||
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| UniProt code: P0A881. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. |
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| Subunit: | |
Homodimer. |
| Subcellular location: | |
Cytoplasm. |
| Similarity: | |
Belongs to the TrpR family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.