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UniProt functional annotation for O30085 | ||
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| UniProt code: O30085. |
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| Organism: | |
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126). |
| Taxonomy: | |
Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae; Archaeoglobus. |
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| Function: | |
Involved in copper export. {ECO:0000269|PubMed:12876283, ECO:0000269|PubMed:22663904}. |
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| Catalytic activity: | |
Reaction=ATP + Cu(2+)(in) + H2O = ADP + Cu(2+)(out) + H(+) + phosphate; Xref=Rhea:RHEA:10376, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29036, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.2.2.9; |
| Activity regulation: | |
Activated by Cu(2+) and to a lesser extent by Ag(+) and Cu(+). {ECO:0000269|PubMed:12763798, ECO:0000269|PubMed:12876283}. |
| Biophysicochemical properties: | |
pH dependence: Optimum pH is 5.7. {ECO:0000269|PubMed:12763798, ECO:0000269|PubMed:12876283}; Temperature dependence: Optimum temperature is 85 degrees Celsius. {ECO:0000269|PubMed:12763798, ECO:0000269|PubMed:12876283}; |
| Subcellular location: | |
Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Domain: | |
The histidine-N-terminal metal-binding domain (His-N-MBD) seems to have a regulatory role affecting the metal transport rate by controlling the metal release/dephosphorylation rates. |
| Similarity: | |
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.