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PDBsum entry 3rdp
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References listed in PDB file
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Key reference
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Title
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Synthesis, Crystal structure, And in vitro biological evaluation of c-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo.
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Authors
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M.Martić,
L.Pernot,
Y.Westermaier,
R.Perozzo,
T.G.Kraljević,
S.Krištafor,
S.Raić-Malić,
L.Scapozza,
S.Ametamey.
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Ref.
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Nucleosides Nucleotides Nucleic Acids, 2011,
30,
293-315.
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PubMed id
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Abstract
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No abstract given.
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Secondary reference #1
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Title
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Nucleoside binding site of herpes simplex type 1 thymidine kinase analyzed by x-Ray crystallography.
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Authors
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J.Vogt,
R.Perozzo,
A.Pautsch,
A.Prota,
P.Schelling,
B.Pilger,
G.Folkers,
L.Scapozza,
G.E.Schulz.
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Ref.
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Proteins, 2000,
41,
545-553.
[DOI no: ]
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PubMed id
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Figure 3.
Figure 3. Structural formulae of the adenosine analogue
9-(2-(S)-hydroxypropyl)adenine (HPA) and the AMP analogue
9-(2-phosphonylmethoxyethyl)adenine (PMEA). HPA was used as a
racemic mixture.
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Figure 6.
Figure 6. Superposition of mutant TK[HSV1](Q125N) in complex
with dT (thick solid lines, C  atoms
marked by small dots, hydrogen bonds are dotted) with wild-type
TK[HSV1] in complex with aciclovir (thin solid lines),[19]
ganciclovir (thin dotted lines)[19]and dT (thick dotted
lines).[19] For sake of clarity, side chains are only drawn for
TK[HSV1](Q125N):dT and TK[HSV1]:aciclovir. Water molecules and
hydrogen bonds are depicted for TK[HSV1](Q125N):dT (black
circles) and TK[HSV1]:aciclovir (pale circles). For aciclovir,
only the location of the hydroxyl group at the 5  -OH
position of dT is shown.
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The above figures are
reproduced from the cited reference
with permission from John Wiley & Sons, Inc.
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