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PDBsum entry 3pqr
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protein ligands Protein-protein interface(s) links
Signaling protein PDB id
3pqr

 

 

 

 

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Contents
Protein chains
326 a.a.
11 a.a.
Ligands
NAG-NAG-BMA-MAN
GLC-GLC
RET
NAG
BOG ×2
PLM
SO4
ACT ×2
Waters ×23
PDB id:
3pqr
Name: Signaling protein
Title: Crystal structure of metarhodopsin ii in complex with a c-terminal peptide derived from the galpha subunit of transducin
Structure: Rhodopsin. Chain: a. Synonym: active metarhodopsin ii with all-trans retinal. Guanine nucleotide-binding protein g(t) subunit alpha-1. Chain: b. Fragment: c-terminal peptide (unp residues 340-350). Synonym: galpha subunit of transducin, transducin alpha-1 chain. Engineered: yes. Mutation: yes
Source: Bos taurus. Bovine. Organism_taxid: 9913. Synthetic: yes. Other_details: chemically synthesized
Resolution:
2.85Å     R-factor:   0.217     R-free:   0.250
Authors: H.-W.Choe,Y.J.Kim,J.H.Park,T.Morizumi,E.F.Pai,N.Krauss,K.P.Hofmann, P.Scheerer,O.P.Ernst
Key ref: H.W.Choe et al. (2011). Crystal structure of metarhodopsin II. Nature, 471, 651-655. PubMed id: 21389988
Date:
26-Nov-10     Release date:   09-Mar-11    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P02699  (OPSD_BOVIN) -  Rhodopsin from Bos taurus
Seq:
Struc: 		348 a.a.
326 a.a.
Protein chain
Pfam   ArchSchema ?
P04695  (GNAT1_BOVIN) -  Guanine nucleotide-binding protein G(t) subunit alpha-1 from Bos taurus
Seq:
Struc: 		350 a.a.
11 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 2 residue positions (black crosses)

 

 
Nature 471:651-655 (2011)
PubMed id: 21389988  
 
 
Crystal structure of metarhodopsin II.
H.W.Choe, Y.J.Kim, J.H.Park, T.Morizumi, E.F.Pai, N.Krauss, K.P.Hofmann, P.Scheerer, O.P.Ernst.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23407534 A.J.Venkatakrishnan, X.Deupi, G.Lebon, C.G.Tate, G.F.Schertler, and M.M.Babu (2013).
Molecular signatures of G-protein-coupled receptors.
  Nature, 494, 185-194.  
23051748 J.F.White, N.Noinaj, Y.Shibata, J.Love, B.Kloss, F.Xu, J.Gvozdenovic-Jeremic, P.Shah, J.Shiloach, C.G.Tate, and R.Grisshammer (2012).
Structure of the agonist-bound neurotensin receptor.
  Nature, 490, 508-513.
PDB code: 4grv
22514183 U.Mueller, N.Darowski, M.R.Fuchs, R.Förster, M.Hellmig, K.S.Paithankar, S.Pühringer, M.Steffien, G.Zocher, and M.S.Weiss (2012).
Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin.
  J Synchrotron Radiat, 19, 442-449.  
21956331 K.Y.Chung, S.G.Rasmussen, T.Liu, S.Li, B.T.DeVree, P.S.Chae, D.Calinski, B.K.Kobilka, V.L.Woods, and R.K.Sunahara (2011).
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor.
  Nature, 477, 611-615.  
21772288 S.G.Rasmussen, B.T.DeVree, Y.Zou, A.C.Kruse, K.Y.Chung, T.S.Kobilka, F.S.Thian, P.S.Chae, E.Pardon, D.Calinski, J.M.Mathiesen, S.T.Shah, J.A.Lyons, M.Caffrey, S.H.Gellman, J.Steyaert, G.Skiniotis, W.I.Weis, R.K.Sunahara, and B.K.Kobilka (2011).
Crystal structure of the β2 adrenergic receptor-Gs protein complex.
  Nature, 477, 549-555.
PDB code: 3sn6
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.

 

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