UniProt functional annotation for P02070

UniProt code: P02070.

Organism: Bos taurus (Bovine).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
 
Function: Involved in oxygen transport from the lung to the various peripheral tissues. {ECO:0000269|PubMed:8343155}.
 
Function: [Spinorphin]: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and may thereby play a role as a regulator of pain and inflammation. {ECO:0000269|PubMed:8343155}.
 
Subunit: Heterotetramer of two alpha chains and two beta chains.
Tissue specificity: Red blood cells.
Polymorphism: Four allelic beta chains have been found in bovine hemoglobins. A and B alleles were found in Jersey cattle and C and D alleles were found in Angoni cattle (East African short-horn zebu). The sequence shown is that of the allele A. {ECO:0000269|PubMed:4561255, ECO:0000269|PubMed:6048711, ECO:0000269|PubMed:6322113}.
Similarity: Belongs to the globin family. {ECO:0000255|PROSITE- ProRule:PRU00238}.

Annotations taken from UniProtKB at the EBI.