UniProt functional annotation for P60438

UniProt code: P60438.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: One of two assembly initiator proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. {ECO:0000269|PubMed:3298242, ECO:0000269|PubMed:6760192}.
 
Subunit: Part of the 50S ribosomal subunit (PubMed:365579, PubMed:10094780, PubMed:12809609, PubMed:16272117, PubMed:25310980, PubMed:24844575, PubMed:27934701, PubMed:27906160, PubMed:27906161). Forms a cluster with proteins L14 and L19. {ECO:0000269|PubMed:10094780, ECO:0000269|PubMed:12809609, ECO:0000269|PubMed:16272117, ECO:0000269|PubMed:24844575, ECO:0000269|PubMed:25310980, ECO:0000269|PubMed:27906160, ECO:0000269|PubMed:27906161, ECO:0000269|PubMed:27934701, ECO:0000269|PubMed:365579}.
Ptm: Methylated by PrmB. {ECO:0000269|PubMed:11847124}.
Mass spectrometry: Mass=22257.2; Method=MALDI; Evidence={ECO:0000269|PubMed:10094780};
Similarity: Belongs to the universal ribosomal protein uL3 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.