PDBsum entry 3o5h

Tunnel analysis for: 3o5h calculated with

MOLE 2.0

PDB id

3o5h

Tunnels calculated on whole structure

Tunnels calculated excluding ligands

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MOLEonline 2.0 manipulation
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visualization
with HETATM:

without HETATM:

29 tunnels, coloured by tunnel radius

29 tunnels, coloured as in
list below

Tunnels are interior spaces connected with the protein surrounding. Only channels longer than 15 Å are shown.

Tunnels

Free R

Length

HPathy

HPhob

Polar

Rel Mut

Residue..type

Ligands

Radius

1.18

99.4

-0.48

-0.71

6.0

A 876 1 C 877 1 G 878 1 C 881 1 C 886 1 G 887 1 A
888 1 U 889 1 G 1450 1 C 1451 1 A 1452 1 A 1453 1
A 1454 1 A 1850 1 U 1888 1 G 1889 1 U 1890 1 A
1891 1 G 1892 1 A 1893 1 U 1894 1 A 1911 1 U 1912
1 C 2118 1 A 2119 1 A 2120 1 U 2334 1 C 2392 1 G
2393 1 G 2394 1 G 2395 1 A 2982 1 C 2983 1 C 2988
1 U 3078 1 C 3082 1 G 3083 1

1.22

101.8

-0.46

-0.70

5.9

A 876 1 C 877 1 G 878 1 C 881 1 C 886 1 G 887 1 A
888 1 U 889 1 G 1450 1 C 1451 1 A 1452 1 A 1453 1
A 1454 1 A 1850 1 U 1888 1 G 1889 1 U 1890 1 A
1891 1 G 1892 1 A 1893 1 U 1894 1 A 1911 1 U 1912
1 A 2113 1 C 2114 1 A 2117 1 C 2118 1 A 2119 1 A
2120 1 C 2392 1 G 2393 1 G 2394 1 G 2395 1 A 2982
1 C 2983 1 C 2988 1 U 3078 1 C 3082 1 G 3083 1

1.20

1.28

107.6

-0.09

-0.47

5.8

C 2392 1 G 2393 1 G 2394 1 G 2395 1 A 2982 1 C
2988 1 U 2989 1 G 2990 1 A 2991 1 U 2992 1 G 2993
1 C 3001 1 C 3002 1 A 3008 1 G 3009 1 A 3139 1 G
3140 1 A 3141 1 C 3143 1 U 3302 1 U 3304 1 C 3311
1 U 3312 1 U 3313 1 A 3314 1 G 3315 1 G 3318 1 U
3319 1 A 3320 1 U 3381 1

1.20

107.2

-0.09

-0.48

5.4

1.18

121.5

-0.19

-0.58

4.8

A 1467 1 A 1468 1 G 1882 1 A 1883 1 C 2392 1 G
2393 1 G 2394 1 G 2395 1 A 2982 1 C 2988 1 U 2989
1 G 2990 1 A 2991 1 U 2992 1 G 2993 1 A 2994 1 A
3000 1 C 3001 1 A 3008 1 G 3009 1 A 3139 1 G 3140
1 A 3141 1 C 3143 1 U 3297 1 C 3298 1 A 3299 1 U
3300 1 G 3309 1 A 3310 1 C 3311 1 U 3312 1

1.19

1.25

125.0

-0.30

-0.59

6.6

G 1882 1 A 1883 1 C 2392 1 G 2393 1 G 2394 1 G
2395 1 A 2982 1 C 2988 1 U 2989 1 G 2990 1 A 2991
1 U 2992 1 G 2993 1 A 2994 1 A 3000 1 C 3001 1 A
3008 1 G 3009 1 A 3139 1 G 3140 1 A 3141 1 C 3143
1 U 3297 1 C 3298 1 A 3299 1 U 3300 1 G 3309 1 A
3310 1 C 3311 1 U 3312 1 G 3390 1 A 3391 1

1.16

129.1

-0.65

-0.57

8.3

A 355 1 A 366 1 A 367 1 A 369 1 U 370 1 A 374 1 A
375 1 G 376 1 A 377 1 U 401 1 A 402 1 C 403 1 C
877 1 G 878 1 G 880 1 C 881 1 G 1450 1 C 1451 1 A
1452 1 A 1504 1 C 1505 1 A 1506 1 G 1507 1 A 1847
1 G 1848 1 C 1849 1 A 1850 1 U 1888 1 G 1889 1 C
2392 1 G 2393 1 G 2394 1 G 2395 1 A 2982 1 C 2983
1 C 2988 1 G 78 3

1.21

129.6

-0.66

-0.59

8.4

1.21

131.2

-0.04

-0.52

4.3

U 1191 1 A 1302 1 U 1305 1 G 1306 1 C 2392 1 G
2393 1 G 2394 1 G 2395 1 G 2830 1 G 2831 1 C 2832
1 A 2833 1 U 2860 1 U 2861 1 U 2862 1 U 2882 1 U
2883 1 C 2884 1 C 2885 1 U 2886 1 A 2887 1 U 2888
1 C 2889 1 G 2907 1 G 2908 1 U 2909 1 A 2910 1 A
2911 1 G 2912 1 G 2922 1 U 2924 1 C 2925 1 A 2926
1 A 2936 1 G 2937 1 G 2938 1 A 2971 1 G 2972 1 A
2982 1 C 2988 1 G 3009 1 U 3010 1 C 3132 1

1.20

132.0

-0.85

-0.67

8.8

C 877 1 G 878 1 G 880 1 C 881 1 G 1450 1 C 1451 1
A 1452 1 U 1495 1 A 1504 1 C 1505 1 A 1506 1 G
1507 1 C 1516 1 G 1517 1 U 1518 1 G 1519 1 G 1520
1 A 1847 1 G 1848 1 C 1849 1 A 1850 1 U 1888 1 G
1889 1 C 2392 1 G 2393 1 G 2394 1 G 2395 1 A 2982
1 C 2983 1 C 2988 1 C 50 3

1.25

132.4

-0.83

-0.67

8.6

1.24

136.9

-0.52

-0.72

6.0

A 876 1 C 877 1 G 878 1 C 881 1 C 886 1 G 887 1 A
888 1 G 1450 1 C 1451 1 A 1452 1 A 1453 1 A 1454
1 U 1463 1 G 1480 1 U 1484 1 G 1485 1 C 1497 1 A
1498 1 C 1499 1 G 1500 1 U 1501 1 U 1512 1 G 1513
1 G 1514 1 U 1840 1 A 1841 1 A 1850 1 U 1876 1 U
1877 1 G 1878 1 U 1888 1 G 1889 1 U 1890 1 A 1891
1 C 2392 1 G 2393 1 G 2394 1 G 2395 1 A 2982 1 C
2983 1 C 2988 1 U 3078 1

1.16

140.9

-0.25

-0.58

5.9

A 409 1 U 410 1 G 421 1 A 1394 1 G 1395 1 C 1396
1 U 1398 1 A 1399 1 G 1409 1 U 1410 1 C 1411 1 G
1421 1 G 1422 1 C 1423 1 G 1444 1 A 2363 1 G 2364
1 G 2385 1 A 2386 1 A 2387 1 U 2388 1 C 2392 1 G
2393 1 G 2394 1 G 2395 1 A 2982 1 C 2985 1 U 2986
1 A 2987 1 C 2988 1 U 2989 1 A 2991 1 A 3008 1 G
3009 1 A 3139 1 C 3143 1 U 5 3 U 6 3 U 7 3 C 8 3

1.16

142.2

-0.14

-0.51

4.6

U 1191 1 A 1193 1 A 1195 1 A 1202 1 A 1203 1 A
1204 1 A 1294 1 G 1295 1 C 1296 1 C 1297 1 C 1298
1 U 1299 1 G 1300 1 A 1301 1 A 1303 1 A 1304 1 U
1305 1 G 1306 1 G 1307 1 A 1308 1 U 1309 1 C 2392
1 G 2393 1 G 2394 1 G 2395 1 U 2882 1 U 2883 1 C
2884 1 C 2885 1 U 2886 1 A 2911 1 G 2912 1 A 2982
1 C 2988 1 G 3009 1 U 3010 1 C 3132 1 C 74 2 G 75
2 A 76 2 A 79 2 U 90 2 G 91 2 A 92 2 C 94 2 A 95
2 C 105 2

1.16

141.5

-0.15

-0.52

4.5

U 1191 1 A 1193 1 A 1195 1 A 1202 1 A 1203 1 A
1204 1 G 1206 1 G 1207 1 U 1208 1 U 1210 1 U 1211
1 G 1213 1 G 1285 1 A 1287 1 U 1288 1 G 1289 1 C
1292 1 U 1293 1 A 1294 1 C 1296 1 C 1297 1 C 1298
1 U 1299 1 G 1300 1 A 1301 1 A 1303 1 A 1304 1 U
1305 1 G 1306 1 G 1307 1 A 1308 1 U 1309 1 C 2392
1 G 2393 1 G 2394 1 G 2395 1 U 2882 1 U 2883 1 C
2884 1 C 2885 1 U 2886 1 A 2911 1 G 2912 1 A 2982
1 C 2988 1 G 3009 1 U 3010 1 C 3115 1 C 3132 1

1.21

141.3

-0.22

-0.57

6.0

1.21

142.9

0.09

-0.34

7.1

A 1129 1 A 1130 1 U 1191 1 C 1199 1 A 1200 1 C
1201 1 A 1303 1 A 1304 1 U 1305 1 G 1306 1 G 1307
1 A 1308 1 U 1309 1 C 2392 1 G 2393 1 G 2394 1 G
2395 1 U 2826 1 U 2827 1 U 2855 1 G 2856 1 U 2858
1 U 2859 1 U 2882 1 U 2883 1 C 2884 1 C 2885 1 U
2886 1 A 2911 1 G 2912 1 A 2982 1 C 2988 1 G 3009
1 U 3010 1 C 3132 1 G 91 2 A 92 2

1.21

142.6

-0.15

-0.50

4.7

1.21

142.0

-0.13

-0.52

4.5

1.25

147.2

-0.18

-0.57

4.6

U 509 1 G 510 1 C 573 1 U 574 1 G 575 1 G 1172 1
U 1173 1 U 1191 1 A 1193 1 G 1194 1 A 1195 1 C
1196 1 A 1202 1 A 1203 1 C 1296 1 C 1297 1 A 1301
1 A 1303 1 A 1304 1 U 1305 1 G 1306 1 G 1307 1 A
1308 1 U 1309 1 G 1321 1 U 1322 1 G 1323 1 U 1324
1 U 1325 1 A 1326 1 C 1327 1 C 2392 1 G 2393 1 G
2394 1 G 2395 1 U 2882 1 U 2883 1 C 2884 1 C 2885
1 U 2886 1 A 2911 1 G 2912 1 A 2982 1 C 2988 1 G
3009 1 U 3010 1 C 3132 1 U 86 2 G 87 2 G 88 2 G
89 2 U 90 2

1.20

146.8

-0.19

-0.58

4.5

1.26

155.6

-0.55

-0.73

6.2

A 876 1 C 877 1 G 878 1 C 881 1 C 886 1 G 887 1 A
888 1 G 1450 1 C 1451 1 A 1452 1 A 1453 1 A 1454
1 G 1480 1 U 1484 1 G 1485 1 G 1486 1 G 1487 1 C
1497 1 G 1514 1 G 1599 1 U 1600 1 U 1601 1 A 1603
1 G 1604 1 A 1752 1 G 1753 1 G 1754 1 G 1766 1 C
1767 1 C 1836 1 U 1837 1 G 1838 1 U 1840 1 A 1841
1 A 1842 1 A 1850 1 U 1876 1 U 1877 1 G 1878 1 U
1888 1 G 1889 1 U 1890 1 A 1891 1 C 2392 1 G 2393
1 G 2394 1 G 2395 1 A 2982 1 C 2983 1 C 2988 1 U
3078 1

1.27

159.9

-0.36

-0.65

6.2

G 33 1 A 34 1 G 277 1 A 807 1 A 808 1 G 809 1 A
810 1 U 811 1 G 812 1 G 908 1 U 922 1 C 923 1 A
926 1 C 927 1 U 1888 1 U 2140 1 C 2392 1 G 2393 1
G 2394 1 G 2395 1 A 2399 1 G 2400 1 A 2401 1 A
2404 1 C 2422 1 U 2423 1 A 2601 1 G 2602 1 A 2811
1 C 2812 1 A 2872 1 G 2874 1 G 2945 1 A 2946 1 G
2947 1 C 2948 1 U 2955 1 U 2978 1 U 2980 1 U 2981
1 A 2982 1 C 2988 1

1.27

165.3

-0.57

-0.72

5.5

A 820 1 U 821 1 G 822 1 A 866 1 G 867 1 C 868 1 G
869 1 G 870 1 A 876 1 C 877 1 G 878 1 C 881 1 U
885 1 C 886 1 G 887 1 A 888 1 A 896 1 U 897 1 U
898 1 U 899 1 A 913 1 G 1450 1 C 1451 1 A 1452 1
A 1453 1 A 1454 1 G 1480 1 U 1484 1 A 1850 1 G
1852 1 G 1868 1 U 1888 1 G 1889 1 U 1890 1 A 1891
1 C 2136 1 A 2138 1 U 2148 1 A 2149 1 G 2150 1 C
2151 1 A 2152 1 U 2153 1 C 2179 1 G 2180 1 C 2181
1 A 2182 1 A 2183 1 U 2184 1 C 2392 1 G 2393 1 G
2394 1 G 2395 1 A 2982 1 C 2983 1 C 2988 1 U 3078
1

1.23

169.3

-0.54

-0.71

5.3

A 820 1 U 821 1 G 822 1 A 866 1 G 867 1 C 868 1 G
869 1 G 870 1 A 876 1 C 877 1 G 878 1 C 881 1 U
885 1 C 886 1 G 887 1 A 888 1 A 896 1 U 897 1 U
898 1 U 899 1 A 913 1 G 1450 1 C 1451 1 A 1452 1
A 1453 1 A 1454 1 G 1480 1 U 1484 1 A 1850 1 G
1852 1 G 1868 1 U 1888 1 G 1889 1 U 1890 1 A 1891
1 C 2136 1 A 2138 1 U 2148 1 A 2149 1 G 2150 1 C
2151 1 A 2152 1 U 2153 1 U 2154 1 C 2179 1 G 2180
1 C 2181 1 A 2182 1 A 2183 1 U 2184 1 C 2392 1 G
2393 1 G 2394 1 G 2395 1 A 2982 1 C 2983 1 C 2988
1 U 3078 1

1.25

175.5

-0.26

-0.59

4.6

G 950 1 A 951 1 A 952 1 G 953 1 U 954 1 G 984 1 A
1103 1 C 1118 1 C 1119 1 A 1120 1 U 1121 1 U 1122
1 U 1124 1 A 1130 1 G 1131 1 A 1133 1 G 1134 1 A
1135 1 A 1136 1 C 1137 1 U 1138 1 G 1139 1 G 1140
1 A 1159 1 U 1191 1 C 1198 1 C 1199 1 A 1200 1 C
1201 1 A 1303 1 A 1304 1 U 1305 1 G 1306 1 G 1307
1 A 1308 1 U 1309 1 A 1363 1 A 1366 1 C 2392 1 G
2393 1 G 2394 1 G 2395 1 U 2826 1 U 2827 1 U 2858
1 U 2859 1 U 2882 1 U 2883 1 C 2884 1 C 2885 1 U
2886 1 A 2911 1 G 2912 1 A 2982 1 C 2988 1 G 3009
1 U 3010 1 C 3132 1 G 91 2 A 92 2

1.28

187.0

-0.21

-0.61

4.1

G 953 1 U 954 1 G 968 1 U 981 1 A 983 1 G 984 1 U
985 1 U 1058 1 G 1059 1 U 1060 1 A 1062 1 G 1063
1 A 1064 1 U 1095 1 A 1098 1 A 1099 1 U 1100 1 C
1118 1 C 1119 1 A 1120 1 U 1121 1 U 1122 1 U 1124
1 A 1130 1 G 1131 1 A 1133 1 G 1134 1 A 1135 1 A
1136 1 C 1137 1 U 1138 1 G 1140 1 U 1191 1 C 1198
1 C 1199 1 A 1200 1 C 1201 1 A 1303 1 A 1304 1 U
1305 1 G 1306 1 G 1307 1 A 1308 1 U 1309 1 C 2392
1 G 2393 1 G 2394 1 G 2395 1 G 2639 1 U 2826 1 U
2827 1 U 2858 1 U 2859 1 U 2882 1 U 2883 1 C 2884
1 C 2885 1 U 2886 1 A 2911 1 G 2912 1 A 2982 1 C
2988 1 G 3009 1 U 3010 1 C 3132 1 G 91 2 A 92 2

1.26

196.7

-0.25

-0.61

5.2

C 729 1 A 952 1 G 953 1 U 954 1 G 968 1 C 969 1 A
970 1 G 971 1 A 972 1 G 974 1 C 975 1 U 976 1 C
977 1 G 978 1 U 979 1 G 984 1 G 1104 1 A 1105 1 G
1106 1 C 1107 1 C 1118 1 C 1119 1 A 1120 1 U 1121
1 U 1122 1 U 1124 1 A 1130 1 G 1131 1 A 1133 1 G
1134 1 A 1135 1 A 1136 1 C 1137 1 U 1138 1 G 1140
1 U 1191 1 C 1198 1 C 1199 1 A 1200 1 C 1201 1 A
1303 1 A 1304 1 U 1305 1 G 1306 1 G 1307 1 A 1308
1 U 1309 1 A 1343 1 G 1344 1 G 1345 1 C 2392 1 G
2393 1 G 2394 1 G 2395 1 U 2826 1 U 2827 1 U 2858
1 U 2859 1 U 2882 1 U 2883 1 C 2884 1 C 2885 1 U
2886 1 A 2911 1 G 2912 1 A 2982 1 C 2988 1 G 3009
1 U 3010 1 C 3132 1 G 91 2 A 92 2

1.28

196.2

-0.25

-0.59

5.2

A 746 1 A 952 1 G 953 1 U 954 1 G 968 1 C 969 1 C
982 1 A 983 1 G 984 1 A 1065 1 G 1066 1 U 1067 1
C 1068 1 A 1084 1 A 1085 1 C 1086 1 G 1106 1 C
1107 1 C 1118 1 C 1119 1 A 1120 1 U 1121 1 U 1122
1 U 1124 1 A 1130 1 G 1131 1 A 1133 1 G 1134 1 A
1135 1 A 1136 1 C 1137 1 U 1138 1 G 1140 1 U 1191
1 C 1198 1 C 1199 1 A 1200 1 C 1201 1 A 1303 1 A
1304 1 U 1305 1 G 1306 1 G 1307 1 A 1308 1 U 1309
1 C 2392 1 G 2393 1 G 2394 1 G 2395 1 U 2826 1 U
2827 1 U 2858 1 U 2859 1 U 2882 1 U 2883 1 C 2884
1 C 2885 1 U 2886 1 A 2911 1 G 2912 1 A 2982 1 C
2988 1 G 3009 1 U 3010 1 C 3132 1 G 91 2 A 92 2

Residue-type_colouring

Positive	Negative	Neutral	Aliphatic	Aromatic	Pro & Gly	Cysteine
H,K,R	D,E	S,T,N,Q	A,V,L,I,M	F,Y,W	P,G	C

Acknowledgement

Tunnels were calculated by

MOLE 2.0 program version 2.5.13.11.08 and visualized using Pymol 0.97rc.