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UniProt functional annotation for Q8TZY2 | ||
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| UniProt code: Q8TZY2. |
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| Organism: | |
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1). |
| Taxonomy: | |
Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus. |
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| Function: | |
Required for chromosome condensation and partitioning (By similarity). Binds single-stranded but not double-stranded DNA. {ECO:0000255|HAMAP-Rule:MF_01894}. |
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| Subunit: | |
Homodimer. {ECO:0000255|HAMAP-Rule:MF_01894, ECO:0000269|PubMed:15458651, ECO:0000269|PubMed:21117236}. |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01894}. |
| Domain: | |
Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible SMC hinge near the middle of the molecule. These domains are separated by coiled- coil structures. The N- and C-terminus interact to make up an ATP- binding cassette-type ATPase domain. The SMC hinge domain mediates dimerization and binds DNA. {ECO:0000255|HAMAP-Rule:MF_01894, ECO:0000269|PubMed:15458651, ECO:0000269|PubMed:21117236}. |
| Similarity: | |
Belongs to the SMC family. {ECO:0000255|HAMAP- Rule:MF_01894}. |
| Sequence caution: | |
Sequence=AAL81967.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.