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UniProt functional annotation for O26232 | ||
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| UniProt code: O26232. |
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| Organism: | |
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum). |
| Taxonomy: | |
Archaea; Euryarchaeota; Methanomada group; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanothermobacter. |
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| Function: | |
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). |
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| Catalytic activity: | |
Reaction=H(+) + orotidine 5'-phosphate = CO2 + UMP; Xref=Rhea:RHEA:11596, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:57538, ChEBI:CHEBI:57865; EC=4.1.1.23; |
| Pathway: | |
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2. |
| Subunit: | |
Homodimer. {ECO:0000269|PubMed:10681441, ECO:0000269|PubMed:11900543, ECO:0000269|PubMed:12011084, ECO:0000269|PubMed:16248642}. |
| Similarity: | |
Belongs to the OMP decarboxylase family. Type 1 subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.