PDBsum entry 3mpv

Membrane protein

PDB id: 3mpv

Contents

Protein chains

200 a.a.

Ligands

BME

Metals

_ZN ×5

Waters ×13

References listed in PDB file

Key reference

Title

Crystallographic insights into the pore structures and mechanisms of the eutl and eutm shell proteins of the ethanolamine-Utilizing microcompartment of escherichia coli.

Authors

M.Takenoya, K.Nikolakakis, M.Sagermann.

Ref.

J Bacteriol, 2010, 192, 6056-6063.

PubMed id

20851901

Abstract

No abstract given.

Secondary reference #1

Title

Crystal structure of the eutl shell protein of the ethanolamine ammonia lyase microcompartment.

Authors

M.Sagermann, A.Ohtaki, K.Nikolakakis.

Ref.

Proc Natl Acad Sci U S A, 2009, 106, 8883-8887. [DOI no: 10.1073/pnas.0902324106]

PubMed id

19451619

Figure 2.
Ribbon diagram of the structures of PduU [PDB ID code 3CGI (only residues 16–122 are shown for clarity)], EutL (C-terminal domain between residues 110 and 216), and Ccmk1 (PDB ID code 3BN4). The structures are displayed in rainbow coloring starting from the N terminus in blue in each case. Helix 1 of EutL is less regularly folded and consists of only 1 helix turn. Even though the overall fold of all proteins is very similar, the order of secondary structure elements is different. Whereas the structures EutL and PduU begin with and N-terminal β-strand (arrows), in the structure of Ccmk1 this strand and former helix 1 are now positioned at the C terminus.

Figure 5.
Representation of the solvent-accessible surface areas of EutL (Left), EutN (Center), and Ccmk1 (Right). In each structure, the monomers are colored differently. Even though EutN is also a hexameric structure, it displays an asymmetric central pore in contrast to Ccmk1. Despite the different functions and origin, all of the structures exhibit a hexagonal tile structure of very similar dimensions and shape.